PcoMed's solutions exploit basic material properties and electrical properties - plus the performance of several lesser explored nano-technologies in order to radically improve performance of medical devices.
Our scientists utilize their expertise in material science, catalysis and advanced physics-based surface construction plus their years of experience in nano-structure fabrication and nano-surface creation.
We exploit a variety of performance variables, such as:
Nano-Topology Controls Cell Attachment
Nano-topology controls the interaction between implanted devices and the cells of the body. PcoMed has discovered that each cell type is attracted to a particular nano-topology and repelled by a partciular range of nano-topologies.
This has allowed PcoMed to create:
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A surface that prevents fibroblasts from attaching to PEEK spinal implants and gets osteoblasts to actually attach to the surface - not simply to grow into nooks and crannies in a porous structure.
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A surface that stimulates endothelial cells to colonize a bare metal coronary stent and prevent blockage of that stent without the use of drugs or degradable polymers.
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A surface to prevent dental implant infections and subsequent failure by:
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Sealing the space between the implant and gum with a surface that encourages gum cells - periodontal ligament fibroblasts and gingival fibroblasts - to attach to the shank of the implant, and
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Sealing the space between the implant and the bone with our TruBōn osteoblast attachment surface.
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AMPLIFYING MEDICAL DEVICE PERFORMANCE
Different Topologies With The Exact Same Material Perform Very Differently
Material Science is an under-utilized area of knowledge in the medical world. PcoMed corrects that oversight and extends material performance even further by using the unique properties of materials at nano-scale.
Material Science and Nano-Scale
Few medical engineers and designers utilize the performance acheivable at material boundaries and
surfaces, such as enhanced electrical transmission on the surface of conductors. Not only does PcoMed exploit that performance, but it extends it even further by dramatically increasing the nano-surface area
of electrical conductors to improve transmission, signal-to-noise ratios and other key performance variables.
Extending Surface Effects For Conductors And Other Products
Catalysis To Avoid Coatings and Elution
By using approaches others haven't tried, we can deliver performance other can't - indefinite anti-thrombosis performance - while avoiding the common problems such as eluting substantances, degradable polymer coatings and the issues and costs associated with applying coatings to catheters and other products.
The Results?
The result of exploiting this and other knowledge is delivering exactly the medical device performance that you want:
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attachment of just the right type of cells to the device
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conductors that outlive the patient
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true bone cell attachment
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polymer-free elution of just the right amount of drug or growth factor at just the right time...
...without the side effects and unwanted complications that plague devices: no infection, no thrombus formation, no conductor failure, no encapsulation, no plastic deformation fatigue...
...all by creating the right surface nano-structure and nano-topology for the performance that you want.
Simple in concept. Very difficult in practice. Amazing when you see our solutions first hand.